Implications of driver genes associated with a high tumor mutation burden identified using next‑generation sequencing on immunotherapy in hepatocellular carcinoma
p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?
Mutant p53 elicits context-dependent pro-tumorigenic phenotypes | Oncogene
Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell Lymphoma | NEJM
p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?
Gaining insights into relevance across cancers based on mutation features of TP53 gene - ScienceDirect
Frontiers | A TP53-Associated Immune Prognostic Signature for the Prediction of Overall Survival and Therapeutic Responses in Muscle-Invasive Bladder Cancer
Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm | ACS Chemical Biology
Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype - ScienceDirect
Cancers | Free Full-Text | TP53 Combined Phenotype Score Is Associated with the Clinical Outcome of TP53-Mutated Myelodysplastic Syndromes
Recent findings on molecular alterations in IDH1, TP53, and CASP9 in gliomagenesis | Biomedical Research and Therapy
The p53 Protein: Mutations, Cancer & Cell Signalling - Assay Genie
TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection - eBioMedicine
Clinical implications of subclonal TP53 mutations in acute myeloid leukemia | Haematologica
Recurrent somatic mutations reveal new insights into consequences of mutagenic processes in cancer | PLOS Computational Biology
Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by transcriptome analysis | Cell Death Discovery
Omics analyses of a somatic Trp53R245W/+ breast cancer model identify cooperating driver events activating PI3K/AKT/mTOR signaling | PNAS
Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden | Genome Medicine | Full Text
An unexpected role for p53 in regulating cancer cell–intrinsic PD-1 by acetylation | Science Advances
Survival of patients with p53 mutations in the DNA-binding motifs... | Download Scientific Diagram
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis | Nature Communications
TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection - eBioMedicine
Targeting a neoantigen derived from a common TP53 mutation | Science
TP53 mutation spectrum in primary colorectal cancers. a Proportion of... | Download Scientific Diagram
Scientists unveil chemotherapy resistance mechanism related to p53 mutation
The function of a heterozygous p53 mutation in a Li-Fraumeni syndrome patient | PLOS ONE
Pathogenesis of TP53-mutated Acute Myeloid leukemia | Laboratory of Daniel C. Link, M.D. | Washington University in St. Louis
